… do not forget to give a host header to the web application. For the web applications that has a port but not a host header as the initial configuration, the portal will not function as it has to. You will not be able to reach the standart configuration pages below /_layouts/ folder and you'll get "File not found" exceptions; if you have mutli language support on the SharePoint farm, some parts of the portal will be served on a different language than the original portal language; and stuff. As I know, there are no hotfixes or patches to solve this situation, so just give a host header name while creating a web application, and get rid of these issues 
kurtlubakla